发明名称 PROCESS FOR PREPARATION OF DRONEDARONE BY N-BUTYLATION
摘要 <p>The invention relates to a novel process for preparation of dronedarone (I) and pharmaceutically acceptable salts thereof where the compound of formula (II) or salt thereof is reacted with a compound of formula L-(CH2)3-CH3 (III), where L is a leaving group, and isolating the obtained product and, if desired, converting it into a pharmaceutically acceptable salt thereof. The invention also relates to some novel intermediary compounds and the preparation thereof.</p>
申请公布号 SG194019(A1) 申请公布日期 2013.11.29
申请号 SG20130073325 申请日期 2012.03.27
申请人 SANOFI 发明人 FRIESZ, ANTAL;PARKANYI, ZSOLT;DOMBRADY, ZSOLT
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