发明名称 |
Use of leptin for treating human lipoatrophy and method of determining predisposition to said treatment |
摘要 |
<p>Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipodystrophy. Leptin is effective against lipodystrophy conditions for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including in a vector comprising nucleic acid sequences encoding leptin. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having approximately 4ng/ml or less before treatment.</p> |
申请公布号 |
SI2219031(T1) |
申请公布日期 |
2013.11.29 |
申请号 |
SI20020031031T |
申请日期 |
2002.10.22 |
申请人 |
AMGEN, INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY;THE BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
DEPAOLI ALEX M;ORAL ELIF ARIOGLU;TAYLOR SIMEON I;GARG A. |
分类号 |
G01N33/53;A61K38/22;A61K38/55;A61K45/00;A61P3/04;A61P3/10;A61P43/00;G01N33/74 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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