| 摘要 |
The present invention relates to a method which makes use of either Ang1 (angiopoietin 1) or COMP-Ang1 (cartilage oligomeric matrix protein-angiopoietin 1), which regulate the differentiation mechanism of stem cells, so as to induce specific differentiation into muscle cells. Provided are a composition which is highly efficient in inducing differentiation from stem cells into muscle cells, and a therapeutic composition for diseases involving muscle damage using the differentiation-inducing ability. Consequently, the outstanding activity of the composition of the present invention can be used to advantage in the alleviation or treatment of diseases involving muscle damage such as muscular dystrophy, muscle inflammation and fibrosis. |
