发明名称 |
PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMIDE |
摘要 |
The present invention relates to a process for the preparation of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl- piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide. Novel solid forms of this compound, their utility in treating diseases caused by deregulated protein kinase activity and pharmaceutical compositions containing them are also object of the present invention |
申请公布号 |
WO2013174876(A1) |
申请公布日期 |
2013.11.28 |
申请号 |
WO2013EP60534 |
申请日期 |
2013.05.22 |
申请人 |
NERVIANO MEDICAL SCIENCES S.R.L. |
发明人 |
BARBUGIAN, NATALE ALVARO;FORINO, ROMUALDO;FUMAGALLI, TIZIANO;ORSINI, PAOLO |
分类号 |
C07D405/12;A61K31/496;A61P35/00 |
主分类号 |
C07D405/12 |
代理机构 |
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