发明名称 |
Cylodextrin complexation methods for formulating peptide proteasome inhibitors |
摘要 |
This disclosure provides methods for formulating compositions comprising one or more peptide proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin. Such methods substantially increase the solubility and stability of these 5 proteasome inhibitors and facilitate both their manufacture and administration. |
申请公布号 |
AU2013204448(A1) |
申请公布日期 |
2013.11.28 |
申请号 |
AU20130204448 |
申请日期 |
2012.09.13 |
申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
LEWIS, EVAN;SHWONEK, PETER;DALZIEL, SEAN;JUMAA, MOUHANNAD |
分类号 |
C07K5/00 |
主分类号 |
C07K5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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