| 发明名称 |
INHIBITORS FOR THE TREATMENT OF CANCER |
| 摘要 |
<p>An isolated peptide comprising a sequence of the N-terminal end of MDM2 that is capable of inhibiting TCTP interaction with p53 and/or MDM2. Also provided is an isolated peptide that is capable of inhibiting MDM2. Also disclosed are nucleic acids, vector, uses, methods of treatment comprising the peptide of the present disclosure and methods of detecting the peptide.</p> |
| 申请公布号 |
WO2013176623(A1) |
申请公布日期 |
2013.11.28 |
| 申请号 |
WO2013SG00208 |
申请日期 |
2013.05.21 |
| 申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) |
发明人 |
GHADESSY, FARID, JOHN;SIAU, JIA WEI;GOH, WALTER;FUNSTON, GARTH |
| 分类号 |
C07K14/435;A61K38/17;A61P35/00;C07H21/04;C12N15/63 |
主分类号 |
C07K14/435 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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