发明名称 |
Antibody having a t-cell receptor-like specificity, yet higher affinity, method of generating same, compositions comprising same and the use of same in the treatment of cancer, viral infection and autoimmune disease |
摘要 |
<p>An isolated molecule which comprises an antibody specifically bindable with a binding affinity below 20 nanomolar, preferably below 10 nanomolar, to a human major histocompatibility complex (MHC) class I being complexed with a HLA-restricted antigen and optionally further comprises an identifiable or therapeutic moiety conjugated to the antibody.</p> |
申请公布号 |
IL193376(A) |
申请公布日期 |
2013.11.28 |
申请号 |
IL20080193376 |
申请日期 |
2008.08.11 |
申请人 |
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.;YORAM REITER;GALIT DENKBERG |
发明人 |
YORAM REITER;GALIT DENKBERG |
分类号 |
A61K;G01N33/53;A61K39/395;A61K47/48;A61P;A61P31/12;A61P37/02;C07K7/06;C07K16/18;C07K16/28;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;G01N33/569;G01N33/574 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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