发明名称 |
METHOD TO DETERMINE RESPONSIVENESS OF CANCER TO EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENTS |
摘要 |
Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
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申请公布号 |
US2013316935(A1) |
申请公布日期 |
2013.11.28 |
申请号 |
US201313896772 |
申请日期 |
2013.05.17 |
申请人 |
THE GENERAL HOSPITAL CORPORATION;DANA FARBER CANCER INSTITUTE, INC.;DANA FARBER CANCER INSTITUTE, INC.;THE GENERAL HOSPITAL CORPORATION |
发明人 |
BELL DAPHNE WINIFRED;HABER DANIEL A.;JANNE PASI ANTERO;JOHNSTON BRUCE E.;LYNCH THOMAS J.;MEYERSON MATTHEW;PAEZ JUAN GUILLERMO;SELLERS WILLIAM R.;SETTLEMAN JEFFREY E.;SORDELLA RAFFAELLA |
分类号 |
C12Q1/68;C12Q1/48;G01N33/574;G01N33/74 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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