发明名称 |
Method for the comparison of a protein under different biological conditions using mass spectrometry |
摘要 |
<p>Optimized enzymatic conditions incorporate a single oxygen atom into digested peptides using a peptidase. The incorporation of a single oxygen atom is especially useful for proteolytic 18O labeling in comparative proteomics. The optimized proteolytic 18O labeling minimizes the generation of a mixture of isotopic isoforms of the peptides resulting from incorporation of either one or two 18O atoms. The outcome is accurate quantification of isotopically labeled peptides.</p> |
申请公布号 |
IL183177(A) |
申请公布日期 |
2013.11.28 |
申请号 |
IL20070183177 |
申请日期 |
2007.05.14 |
申请人 |
UNIVERSITY OF NORTH DAKOTA |
发明人 |
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分类号 |
C12N;C12P;C12Q;G01N |
主分类号 |
C12N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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