DIFFERENTIAL EXPRESSION OF MICRORNAS IN NONFAILING VERSUS FAILING HUMAN HEARTS
摘要
<p>The present invention discloses specific miRNAs as novel biomarkers and therapeutic targets in the treatment of heart failure. Methods of treating or preventing heart failure in a subject by administering mimics or inhibitors of these particular miRNAs are disclosed. A method of diagnosing or prognosing heart failure in a subject by determining the level of expression of one or more miRNAs is also described.</p>
申请公布号
EP2179060(B1)
申请公布日期
2013.11.27
申请号
EP20080796304
申请日期
2008.07.18
申请人
THE REGENTS OF THE UNIVERSITY OF COLORADO
发明人
PORT, JONATHAN DAVID;SUCHAROV, CARMEN;BRISTOW, MICHAEL R.