发明名称 DETECTION OF DIFFERENT TARGET COMPONENTS BY CLUSTER FORMATION
摘要 <p>The invention relates to a method, a test kit, and an apparatus (100) for detecting a plurality of different species of target components (T1, T2) in a sample. This is achieved by using a plurality of classes of label particles (1, 2), wherein at least one of the label particles (1, 2) in each class is a magnetic particle, and wherein label particles (1, 2) from each class can bind to each other via the same class-specific species of target component. Clusters of label particles (1, 2) can then form in which binding to specific target components (T1, T2) is accompanied by characteristic properties, for example magnetic susceptibilities of the associated label particles (1, 2). The selective actuation of such clusters by a magnetic field (B) with at least one oscillating component and a variable field amplitude together with the detection of such selectively actuated clusters will hence allow to specifically detect the clusters. This provides information about the different target components (T1, T2) in the sample.</p>
申请公布号 EP2467722(B1) 申请公布日期 2013.11.27
申请号 EP20100752428 申请日期 2010.08.16
申请人 KONINKLIJKE PHILIPS N.V. 发明人 RANZONI, ANDREA;OVSYANKO, MIKHAIL, MIKHAYLOVICH;PRINS, MENNO, WILLEM, JOSE
分类号 G01N33/543 主分类号 G01N33/543
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