发明名称 |
PARTICLE COMPOSITION AND MEDICINAL COMPOSITION COMPRISING SAME |
摘要 |
The present invention provides a particulate composition containing: block copolymer units being arranged radially with hydrophobic polymer-chain segments radially inside and hydrophilic polymer-chain segments radially outside; and a charged lipid which carries a charge opposite to the charge of a drug to be encapsulated, the charged lipid being attracted to the hydrophobic polymer-chain segment. In this particulate composition, the drug is retained within the particle via electrostatic binding with the charged lipid, whereby the outer surface of the particle is prevented from being charged to attract a substance which has a charge opposite to that of the charged lipid. |
申请公布号 |
EP2474306(A4) |
申请公布日期 |
2013.11.27 |
申请号 |
EP20100812082 |
申请日期 |
2010.08.31 |
申请人 |
NANOCARRIER CO., LTD. |
发明人 |
KATO, YASUKI;ISHII, ATSUSHI |
分类号 |
A61K9/10;A61K9/16;A61K31/7088;A61K31/715;A61K38/00;A61K47/34;A61K47/44 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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