发明名称 PHARMACEUTICAL COMPOSITION FOR TREATING EAR DISEASES
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine. A composition for treating an ear disease is introduced into the tympanic cavity, contains a polyoxyethylene-polyoxypropylene copolymer, an active substance specified in an immunomodulator, a vasopressin antagonist, an ion channel antagonist, a neurokinin receptor antagonist, a serotonin reuptake inhibitor, an NMDA-receptor antagonist, a prostaglandin analogue, a preparation having an effect on the central nervous system, a GABA receptor modulator, a cytotoxic agent, an antioxidant, a glutamate receptor modulator or a calcineurin inhibitor.EFFECT: invention provides the prolonged release of the active substance into the internal ear for a period of time of at least 7 days.14 cl, 3 dwg, 114 ex
申请公布号 RU2499592(C2) 申请公布日期 2013.11.27
申请号 RU20100147298 申请日期 2009.04.21
申请人 OTONOMI, INK.;DZE REGENTS OF DZE JUNIVERSITI OF KALIFORNIJA 发明人 LIKHTER DZHEJ;FOLL'RAT BENEDIKT;TREHMMEL EHNDRJU M.;DJURON SERGIO G.;P'JU FABRIS;DELLAMEHRI LUIS A.;E TSJAN;LEBEL KARL;SKAJF MAJKL KRISTOFER;KHARRIS DZHEFFRI P.
分类号 A61K9/10;A61K9/06;A61K39/395;A61K47/48;A61P27/16 主分类号 A61K9/10
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