Holographic imaging for analyzing molecules

摘要

The present invention provides a device (100) for analyzing target molecules. The device comprises a substrate retention device for holding a substrate (3) having a functionalized surface (10) provided thereon. This functionalized surface is adapted for capturing a plurality of target molecules. The device also comprises a light source (1) for illuminating the functionalized surface and an image sensor (4) for recording interference patterns of magnetic particles (2) present on the functionalized surface (10). The device further comprises a first magnetic field generator (6) configured to generate a magnetic field to attract magnetic particles (2) linked to the target molecules to the functionalized surface (10). The invention further relates to a method (200) for analyzing target molecules.