| 摘要 |
<p>The invention provides LTBP2, which is associated with cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of LTBP2 as well as pharmaceutical compositions comprising such compounds. The invention also provides LTBP2 as a biomarker for diseases such as cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases.</p> |
| 申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
GOLZ, STEFAN;SUMMER, HOLGER;GEERTS, ANDREAS;BRUEGGEMEIER, ULF;ALBRECHT-KUEPPER, BARBARA;KLEIN, MARTINA;STEPPAN, SONJA;ELLINGHAUS, PETER;D'URSO, DONATELLA;SEEWALD, MICHAEL;MILTING, HENDRIK |
