The present disclosure provides antibody-drug conjugates that are potent cytotoxins, wherein the drug is linked to the antibody through a linker. The disclosure is also directed to compositions containing the antibody-drug conjugates, and to methods of treatment using them.
申请公布号
CA2623652(C)
申请公布日期
2013.11.26
申请号
CA20062623652
申请日期
2006.09.26
申请人
MEDAREX, INC.
发明人
BOYD, SHARON ELAINE;CHEN, LIANG;GANGWAR, SANJEEV;GUERLAVAIS, VINCENT;HORGAN, KILIAN;SUFI, BILAL;CARDARELLI, JOSEPHINE M.;PAN, CHIN;HUANG, HAICHUN;KING, DAVID JOHN
