发明名称 |
RECOMBINANT NUCLEIC ACIDS COMPRISING REGIONS OF AD6 |
摘要 |
The present invention features Ad6 vectors and a nucleic acid encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing an inactive NS5B RNA-dependent RNA polymerase region. The nucleic acid is particularly useful as a component of an adenovector or DNA plasmid vaccine providing a broad range of antigens for generating an HCV specific cell mediated immune (CMI) response against HCV. |
申请公布号 |
CA2718802(C) |
申请公布日期 |
2013.11.26 |
申请号 |
CA20022718802 |
申请日期 |
2002.10.10 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
KASLOW, DAVID C.;BETT, ANDREW J. |
分类号 |
C12N15/861;A61K39/39;A61K48/00;C07K14/18;C12N15/51;C12N15/85 |
主分类号 |
C12N15/861 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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