| 发明名称 |
WT1 FUSION POLYPEPTIDES AND METHODS FOR WT1 IMMUNOTHERAPY |
| 摘要 |
Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; or a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases. |
| 申请公布号 |
CA2425072(C) |
申请公布日期 |
2013.11.26 |
| 申请号 |
CA20012425072 |
申请日期 |
2001.10.03 |
| 申请人 |
CORIXA CORPORATION;GAIGER, ALEXANDER |
发明人 |
MCNEILL, PATRICIA D.;SMITHGALL, MOLLY;MOULTON, GUS;VEDVICK, THOMAS S.;SLEATH, PAUL R.;MOSSMAN, SALLY;EVANS, LAWRENCE;SPIES, A. GREGORY;BOYDSTON, JEREMY;GAIGER, ALEXANDER |
| 分类号 |
A61K38/16;G01N33/574;A61K31/7088;A61K35/14;A61K38/00;A61K38/17;A61K39/00;A61K39/39;A61K39/395;A61K45/00;A61K48/00;A61P35/00;A61P35/02;A61P37/04;C07H21/02;C07H21/04;C07K14/435;C07K14/47;C07K14/82;C07K16/32;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/68;G01N33/53 |
主分类号 |
A61K38/16 |
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