发明名称 |
Compositions and methods including cell death inducers and procaspase activation |
摘要 |
Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed in connection with modification of procaspases such as procaspase-3. In embodiments, compositions are capable of activation of procaspase-3.
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申请公布号 |
US8592584(B2) |
申请公布日期 |
2013.11.26 |
申请号 |
US201113087595 |
申请日期 |
2011.04.15 |
申请人 |
HERGENROTHER PAUL J.;PUTT KARSON S.;PETERSON QUINN P.;FAKO VALERIE;THE BOARD OF TRUSTEES OF THE OF THE UNIVERSITY OFILLINOIS |
发明人 |
HERGENROTHER PAUL J.;PUTT KARSON S.;PETERSON QUINN P.;FAKO VALERIE |
分类号 |
A61K31/495;C07D211/34;C07D211/62;C07D241/04;C07D295/13;C07D295/15;C07D401/06;C07D403/12 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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