发明名称 |
NOVEL NI COMPLEX AND ITS DERIVATIVES, PRODUCING METHOD, AND THE USE THEREOF AS ANTIOXIDANT |
摘要 |
The present invention relates to a novel nickel complex and its derivatives, which mimic the active site of Ni-containing superoxide dismutase (NiSOD). The five-coordinate Ni(II) and Ni(III) complexes or their derivatives, and six-coordinate derivatives have the following structures of formula (I) and (II): (see formula I) (see formula II) The nickel complexes and their derivatives of the invention act as anti-oxidants or free radical scavengers. The invented nickel complexes can be used in the preparation of medicines, health foods or cosmetics for human, animals and plants, or can be used in environmental or soil protection. |
申请公布号 |
CA2788470(A1) |
申请公布日期 |
2013.11.22 |
申请号 |
CA20122788470 |
申请日期 |
2012.08.24 |
申请人 |
NATIONAL TAIWAN NORMAL UNIVERSITY |
发明人 |
LEE, WAY-ZEN;CHIANG, CHIEN-WEI;LIN, TSUNG-HAN;KUO, TING-SHEN |
分类号 |
C07D401/14;A61K8/19;A61K8/49;A61K31/33;A61K31/4439;A61P39/06;C07F7/08;C09K15/32 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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