发明名称 |
Benzotiazoles y tiazolopiridinas como moduladores de la sirtuína |
摘要 |
Provided herein are novel sirtuin-modulating compounds (XII) and (XIII). The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
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申请公布号 |
ES2431050(T3) |
申请公布日期 |
2013.11.22 |
申请号 |
ES20060789433T |
申请日期 |
2006.08.04 |
申请人 |
SIRTRIS PHARMACEUTICALS, INC. |
发明人 |
NUNES, JOSEPH;MILNE, JILL;BEMIS, JEAN;XIE, ROGER;VU, CHI;NG, PUI;DISCH, JEREMY;SALZMANN, THOMAS;ARMISTEAD, DAVID |
分类号 |
C07D235/18;A61K31/41;A61K31/435;A61K31/495;C07D401/12;C07D403/12;C07D513/04 |
主分类号 |
C07D235/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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