| 摘要 |
PROBLEM TO BE SOLVED: To provide a coating for a medical device comprising cross-linked fatty acids and glycerides.SOLUTION: Fatty acid-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming the biomaterials and tailoring the properties of the biomaterials, and methods of using the biomaterials for treating injury in a mammal are also provided. In various aspects, the present invention may provide methods for producing a hydrophobic, cross-linked fatty acid-derived biomaterial (e.g., a medical device coating or stand-alone film) that can be utilized alone or in combination with one or more therapeutic agents. |
