PAPAYA MOSAIC VIRUS-BASED INFLUENZA ANTIGEN PRESENTING SYSTEM AND INFLUENZA VACCINE CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a papaya mosaic virus-based vaccine against influenza.SOLUTION: An antigen-presenting system includes one or more influenza virus antigens in combination with a papaya mosaic virus (PapMV) or a virus-like particle (VLP) containing a PapMV coat protein. At least one of influenza virus antigens is derived from an influenza virus nucleic protein (NP) and is not conjugated to the PapMV or VLP.