| 发明名称 |
MIR-21 PROMOTER DRIVEN TARGETED CANCER THERAPY |
| 摘要 |
The invention provides a nucleic acid construct comprising a promoter sequence derived from microRNA-21 (miR-21) linked to a nucleic acid sequence encoding an anti-cancer agent, an example of which is a toxin. The constructs of the invention are particularly useful for treating tumors expressing miR-21.
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| 申请公布号 |
US2013310446(A1) |
申请公布日期 |
2013.11.21 |
| 申请号 |
US201313942394 |
申请日期 |
2013.07.15 |
| 申请人 |
RAMOT AT TEL AVIV UNIVERSITY, LTD. |
发明人 |
ROSIN-ARBESFELD RINA;SKLAN ELLA;ZILBERBERG ALONA;DAVID NAAMA |
| 分类号 |
A61K48/00;A61K38/16;C12N15/85 |
主分类号 |
A61K48/00 |
| 代理机构 |
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