发明名称 |
Fused imidazole derivatives useful as IDO inhibitors |
摘要 |
<p>Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated inimunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease.</p> |
申请公布号 |
AU2012242871(A8) |
申请公布日期 |
2013.11.21 |
申请号 |
AU20120242871 |
申请日期 |
2012.04.12 |
申请人 |
NEWLINK GENETICS CORPORATION |
发明人 |
MAUTINO, MARIO;KUMAR, SANJEEV;WALDO, JESSE;JAIPURI, FIROZ;KESHARWANI, TANAY;ZHANG, XIAOXIA |
分类号 |
C07D487/04;A61K31/4188;A61P37/02 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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