发明名称 |
Immune modulation via C-type lectin |
摘要 |
<p>The invention relates to the regulation of the immune system, and in particular to the finding that the CLEC9a molecule is a marker for dendritic cells which are capable of cross-presenting extracellular antigens via the MHC class I pathway. This makes them particularly suitable for generation of cytotoxic T lymphocyte responses. Materials and methods are provided both for the induction of immune responses against target antigens, and for the inhibition or suppression of undesirable immune responses in which these cells are involved.</p> |
申请公布号 |
AU2008278831(B2) |
申请公布日期 |
2013.11.21 |
申请号 |
AU20080278831 |
申请日期 |
2008.07.21 |
申请人 |
CANCER RESEARCH TECHNOLOGY LIMITED |
发明人 |
REIS E. SOUSA, CAETANO;PENNINGTON, DANIEL;SCHULZ, OLIVER;JOFFRE, OLIVIER PIERRE;SANCHO-MADRID, DAVID;ROGERS, NEIL CHARLES |
分类号 |
C07K14/705;A61K38/00;A61K47/00;C07K14/47;C07K16/28 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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