发明名称 |
Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same |
摘要 |
There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous composition that comprises a lipophilic pharmaceutical agent, and an amphiphilic polymeric solvent such as PEG400 but essentially free of organic solvents and non-solubilized particles. The composition may be further diluted with a desired aqueous diluent such as an infusion fluid for parenteral administration to a subject such as a human. The compositions may be useful for the treatment for diseases or conditions that are sensitive to lipophilic agents, such as infectious diseases, malignant or autoimmune diseases. |
申请公布号 |
AU2012250050(A1) |
申请公布日期 |
2013.11.21 |
申请号 |
AU20120250050 |
申请日期 |
2012.04.20 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
ANDERSSON, BORJE S.;VALDEZ, BENIGNO C.;TARRAND, JEFFREY |
分类号 |
A61K9/107;A61K9/00;A61K47/10 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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