发明名称 SUBSTRATE MEDIATED ENZYMES PRODRUG THERAPY
摘要 A method is provided for administering an active drug agent to cells adhering and/or adjacent to a substrate, said substrate comprising one or more immobilized enzymes, which are capable of converting an inert prodrug into an active drug agent, said method comprising providing at least one inactive prodrug to said substrate. Also a kit is provided which comprise a substrate comprising one or more immobilized enzymes capable of converting an inert prodrug into an active drug agent, and at least one inert prodrug. A stent is also provided, which comprise a substrate comprising one or more immobilized enzymes capable of converting an inert prodrug into an active drug agent.
申请公布号 WO2013170862(A1) 申请公布日期 2013.11.21
申请号 WO2013DK50152 申请日期 2013.05.21
申请人 AARHUS UNIVERSITET 发明人 ZELIKIN, ALEXANDER;KRISTENSEN, BETINA FEJERSKOV
分类号 A61K47/48;A61L27/16;A61L27/36;A61L31/04;A61P9/10 主分类号 A61K47/48
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