发明名称 Combinations of AKT and MEK inhibitor compounds, and methods of use
摘要 The invention provides combinations comprising a) compound of formula I : (formula I), or a pharmaceutically acceptable salt thereof; and another agent selected from GDC-0973, PD-0325901, or a pharmaceutically acceptable salt thereof. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer.
申请公布号 AU2012236164(A1) 申请公布日期 2013.11.21
申请号 AU20120236164 申请日期 2012.03.30
申请人 GENENTECH, INC. 发明人 LEE, BRIAN;LIN, KUI;NANNINI, MICHELLE;PUNNOOSE, ELIZABETH;SAMPATH, DEEPAK
分类号 C07D239/70;A61K31/517 主分类号 C07D239/70
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