发明名称 PHARMACEUTICAL COMPOSITION COMPRISING (1R,4R)-6'-FLUORO-N,N-DIMETHYL-4-PHENYL-4',9'-DIHYDRO-3'H-SPIRO[CYCLOHEXANE-1,1'-PYRANO [3,4,B]INDOL]-4-AMINE AND A NSAR
摘要 The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient selected from (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and the physiologically acceptable salts thereof, and a second pharmacologically active ingredient which is a non-steroidal antirheumatic drug selected from the group consisting of indometacin, diclofenac, sulindac, tolmetin, zomepirac, aclofenac, bumadizone, etodolac, lonazolac, fentiazac, acemetacin, difenpiramide, oxametacin, proglumetacin, ketorolac, aceclofenac, bufexamac, mefenamic acid, tolfenamic acid, flufenamic acid, meclofenamic acid, and the physiologically acceptable salts thereof.
申请公布号 WO2013170971(A1) 申请公布日期 2013.11.21
申请号 WO2013EP01470 申请日期 2013.05.16
申请人 GRUENENTHAL GMBH 发明人 FROSCH, STEFANIE;LINZ, KLAUS;SCHIENE, KLAUS
分类号 A61K31/407;A61K31/196;A61K31/405;A61K45/06;A61P19/00;A61P25/00;A61P29/00 主分类号 A61K31/407
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