Compositions of recombinant HSV-2 proteins and an agonist of the innate immune system, such as an adjuvant, are provided as a vaccine. Proteins include an envelope glycoprotein and a structural protein other than an envelope glycoprotein, e.g., a capsid or tegument protein. The vaccine is for use in either HSV-2 seropositive or seronegative subjects.
申请公布号
WO2013173590(A1)
申请公布日期
2013.11.21
申请号
WO2013US41364
申请日期
2013.05.16
申请人
IMMUNE DESIGN CORP.
发明人
DUBENSKY, THOMAS, W., JR.;HOSKEN, NANCY, A.;ROBBINS, SCOTT, H.;MOORE, MARGARET, D.