发明名称 |
Immune-modulating peptide |
摘要 |
<p>Disclosed are peptides having SEQ ID NOs: 1 to 24 that induce superoxide generation by human monocytes or neutrophils; that induce an intracellular calcium increase by human peripheral blood monocytes or neutrophils; binds to formyl peptide receptor or formyl peptide receptor-like 1; that induce chemotactic migration of human monocytes or neutrophils in vitro; that induce degranulation in formyl peptide receptor expressing cells or formyl peptide receptor-like 1 expressing cells; that stimulate extracellular signal regulated protein kinase phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1; or that stimulate Akt phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1.</p> |
申请公布号 |
EP2108655(B1) |
申请公布日期 |
2013.11.20 |
申请号 |
EP20090156973 |
申请日期 |
2003.01.28 |
申请人 |
POSCO;POSTECH FOUNDATION |
发明人 |
RYU, SUNG-HO;SUH, PANN-GHILL;BAE, YOE-SIK;SONG, JI-YOUNG |
分类号 |
C07K7/06;C12N15/09;A61K38/00;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/14;A61P19/02;A61P19/10;A61P25/00;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/06;C07K5/083;C07K5/107;C07K5/11 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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