发明名称 |
CORNEAL DELIVERY OF CROSS-LINKING AGENTS BY IONTOPHORESIS FOR THE TREATMENT OF KERATOCONUS AND RELATED OPHTHALMIC COMPOSITIONS |
摘要 |
Iontophoresis for delivering ophthalmic compositions (in particular. collyriums) preferably containing riboflavin, or other cross-linking agents, designed to imbibe the corneal stroma in the practice of the corneal collagen cross-linking (CXL) for the keratoconus treatment, and the corresponding ophthalmic compositions adapted to be administrated by iontophoresis in the treatment of keratoconus by corneal collagen cross-linking. Additionally, an ophthalmic composition for the treatment of keratoconus by corneal iontophoresis characterized by the fact that it includes cross-linking agents having buffering properties and whose initial pH value is included between 5 and 6, and/or bio-enhancers, and/or photo-enhancers. |
申请公布号 |
EP2663281(A1) |
申请公布日期 |
2013.11.20 |
申请号 |
EP20110709197 |
申请日期 |
2011.01.12 |
申请人 |
SOOFT ITALIA S.P.A. |
发明人 |
FOSCHINI, FULVIO;ROY, PIERRE;STAGNI, EDOARDO;CAVALLO, GIOVANNI;LUCIANI, GIULIO |
分类号 |
A61K9/00;A61K31/525 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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