发明名称 |
NOVEL HYALURONIC ACID DECOMPOSITION-PROMOTING FACTOR AND INHIBITOR THEREOF |
摘要 |
<p>The present invention is directed to KIAA1199, which is a novel factor involved in decomposition of hyaluronic acid, and to use thereof. More specifically, the invention is directed to a hyaluronic acid decomposition-promoting agent containing the KIAA1199 gene and a protein encoded by the gene; to a hyaluronic acid decomposition-inhibiting agent characterized by inhibiting the activity or expression thereof (including an siRNA or a monoclonal antibody); and to a method for screening a novel hyaluronic acid decomposition-controlling agent, in which the method contains employing the expression of KIAA1199 as an index.</p> |
申请公布号 |
EP2594274(A4) |
申请公布日期 |
2013.11.20 |
申请号 |
EP20110789484 |
申请日期 |
2011.06.03 |
申请人 |
KAO CORPORATION |
发明人 |
YOSHIDA, HIROYUKI;INOUE, SHINTARO;SAKAI, SHINGO;NAGAOKA, AYA |
分类号 |
A61K31/7088;A61K8/40;A61K8/42;A61K8/49;A61K8/73;A61K31/365;A61K31/4015;A61K31/5415;A61K31/713;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P17/02;A61P17/16;A61P19/02;A61P27/16;A61P35/00;A61P43/00;A61Q19/00 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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