摘要 |
An instrument and associated method are disclosed for the accelerated synthesis of peptides by the solid phase method. The instrument includes a microwave cavity, a microwave source in communication with the cavity, a column (43) in the cavity formed of a material that is transparent to microwave radiation, a solid phase peptide support resin in the column, respective filters for maintaining the solid phase support resin in the column, a first passageway (46) for adding starting compositions to the column, a second passageway (47) for removing compositions from the column, and a third passageway (50) for circulating compositions from the column into the third passageway and back to the column.
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