发明名称 METHOD FOR MEASUREMENT OF CONCENTRATION OF ANTIGEN
摘要 <p>The object of the present invention is to provide a detection method that can detect an antigen even if the target antigen has a low molecular weight in a simpler, more efficient, and more stable manner and with higher sensitivity. The detection of the antigen is carried out by using a fusion protein comprising a polypeptide containing a V H domain of an antibody; a given protein; a linker peptide; a partner protein having an activity of binding to the protein and capable of detecting binding to the protein; and a polypeptide containing a V L domain of the antibody; in this order or in inverse order to this order, wherein the presence or absence of the binding of the polypeptide containing a V H domain and the polypeptide containing a V L domain to the antigen induces the presence or absence of the binding of the protein and the partner protein.</p>
申请公布号 EP2177611(B1) 申请公布日期 2013.11.20
申请号 EP20080790313 申请日期 2008.07.30
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 UEDA, HIROSHI;KOJIMA, MIKI
分类号 C12N15/09;C07K16/00;C07K16/18;C07K16/40;C07K16/44;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/86;G01N21/78;G01N33/53;G01N33/542;G01N33/68 主分类号 C12N15/09
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