发明名称 |
METHOD FOR MEASUREMENT OF CONCENTRATION OF ANTIGEN |
摘要 |
<p>The object of the present invention is to provide a detection method that can detect an antigen even if the target antigen has a low molecular weight in a simpler, more efficient, and more stable manner and with higher sensitivity. The detection of the antigen is carried out by using a fusion protein comprising a polypeptide containing a V H domain of an antibody; a given protein; a linker peptide; a partner protein having an activity of binding to the protein and capable of detecting binding to the protein; and a polypeptide containing a V L domain of the antibody; in this order or in inverse order to this order, wherein the presence or absence of the binding of the polypeptide containing a V H domain and the polypeptide containing a V L domain to the antigen induces the presence or absence of the binding of the protein and the partner protein.</p> |
申请公布号 |
EP2177611(B1) |
申请公布日期 |
2013.11.20 |
申请号 |
EP20080790313 |
申请日期 |
2008.07.30 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
UEDA, HIROSHI;KOJIMA, MIKI |
分类号 |
C12N15/09;C07K16/00;C07K16/18;C07K16/40;C07K16/44;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/86;G01N21/78;G01N33/53;G01N33/542;G01N33/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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