| 发明名称 |
Modified iRNA agents |
| 摘要 |
The invention relates to a metod for preparing iRNA agents having partial complementary to their target RNA by including at leat one mismatch within the 6 terminal nucleotides of either end of the antisense strand. |
| 申请公布号 |
EP2664672(A1) |
申请公布日期 |
2013.11.20 |
| 申请号 |
EP20130003404 |
申请日期 |
2004.04.16 |
| 申请人 |
ALNYLAM PHARMACEUTICALS INC. |
发明人 |
MANOHARAN, MUTHIAH |
| 分类号 |
C12N15/113;A61K31/70;A61K31/713;A61K48/00;C07D473/14;C07H21/02;C07H21/04;C12N;C12Q1/68 |
主分类号 |
C12N15/113 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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