发明名称 Virus vector and use thereof
摘要 It is intended to provide a polynucleotide comprising a viral base sequence, the viral base sequence containing: a first base sequence encoding a viral replication protein, and a second base sequence encoding a viral movement protein, the second base sequence being located downstream of the first base sequence and having a linking site for linking with an exogenous base sequence encoding a polypeptide to be expressed, the linking site being located downstream of the second base sequence, the second base sequence being obtained by modifying with a base sequence in a native sequence derived from a virus by insertion, substitution, or addition. By using this, a vector containing a viral base sequence is constructed, and a protein is efficiently produced without worsening growth of a host cell containing the vector.
申请公布号 US8586826(B2) 申请公布日期 2013.11.19
申请号 US20080450999 申请日期 2008.04.11
申请人 MORI MASASHI;DOHI KOJI;JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 MORI MASASHI;DOHI KOJI
分类号 C07K14/005;C12N15/40;C12N15/67 主分类号 C07K14/005
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