发明名称 |
Novel crystalline forms of a dipeptidyl peptidase-IV inhibitor |
摘要 |
Novel crystalline forms of (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine are potent inhibitors of dipeptidyl peptidase-IV and are useful for the treatment of non-insulin dependent (Type 2) diabetes mellitus. The invention also relates to pharmaceutical compositions containing these novel forms, processes to prepare these forms and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes. |
申请公布号 |
AU2012275637(A1) |
申请公布日期 |
2013.11.14 |
申请号 |
AU20120275637 |
申请日期 |
2012.06.25 |
申请人 |
MERCK SHARPE & DOHME LTD.;MERCK SHARP & DOHME CORP. |
发明人 |
ARROYO, ITZIA;KRUEGER, DAVIDA;CHEN, PING;MOMENT, AARON;BIFTU, TESFAYE;SHEEN, FAYE;ZHANG, YANFENG |
分类号 |
A61K31/4439;A61K31/4985;A61K31/513 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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