发明名称 Novel crystalline forms of a dipeptidyl peptidase-IV inhibitor
摘要 Novel crystalline forms of (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine are potent inhibitors of dipeptidyl peptidase-IV and are useful for the treatment of non-insulin dependent (Type 2) diabetes mellitus. The invention also relates to pharmaceutical compositions containing these novel forms, processes to prepare these forms and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes.
申请公布号 AU2012275637(A1) 申请公布日期 2013.11.14
申请号 AU20120275637 申请日期 2012.06.25
申请人 MERCK SHARPE & DOHME LTD.;MERCK SHARP & DOHME CORP. 发明人 ARROYO, ITZIA;KRUEGER, DAVIDA;CHEN, PING;MOMENT, AARON;BIFTU, TESFAYE;SHEEN, FAYE;ZHANG, YANFENG
分类号 A61K31/4439;A61K31/4985;A61K31/513 主分类号 A61K31/4439
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