发明名称 COMBINATION THERAPY OF A MEK INHIBITOR AND IGF1R INHIBITOR
摘要 The present invention relates to a pharmaceutical combination comprising a MEK inhibitor compound 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)- amide or a pharmaceutically acceptable salt thereof and the IGF1R inhibitor ANTIBODY A, a pharmaceutical composition comprising such combination, methods for treating cancer comprising administration of a therapeutically effective amount of such combination to a subject in need thereof, and uses of such combination for the treatment of cancer.
申请公布号 WO2013142182(A3) 申请公布日期 2013.11.14
申请号 WO2013US30781 申请日期 2013.03.13
申请人 NOVARTIS PHARMA AG;AMGEN INC. 发明人 HUANG, XIZHONG;PETERS, MALTE;SCHUMACHER, KARL, MARIA;CAO, ZHU, ALEXANDER;GANSERT, JENNIFER, LORRAINE;CHANG, DAVID, DONG, EUN;BELTRAN, PEDRO
分类号 A61K39/395;C07K16/28 主分类号 A61K39/395
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