发明名称 |
UNIQUELY SPECIFIC PROBES FOR PTEN, PIK3CA, MET, TOP2A, AND MDM2 |
摘要 |
Disclosed herein are nucleic acid probes comprising a plurality of segments of uniquely specific nucleic acid sequences. In some examples, the nucleic acid probes include or consist of a nucleic acid sequence set forth as any one of SEQ ID NOs: 1-50. The disclosed probes are useful for detecting presence of a target nucleic acid in a sample. In some embodiments, the probes are useful for detecting presence of phosphatase and tensin homolog (PTEN), phosphatidylinositol 3-kinase p110 (PIK3CA), mouse double minute 2 (MDM2), Met proto-oncogene (MET), or topoisomerase II alpha (TOP2A) in a sample. |
申请公布号 |
WO2013167387(A1) |
申请公布日期 |
2013.11.14 |
申请号 |
WO2013EP58584 |
申请日期 |
2013.04.25 |
申请人 |
VENTANA MEDICAL SYSTEMS, INC.;F. HOFFMANN-LA ROCHE AG |
发明人 |
ALEXANDER, NELSON;GRILLE, JAMES;STANISLAW, STACEY |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|