发明名称 |
MEDICAMENT, METHOD, AND DRUG DELIVERY DEVICE FOR TREATMENT OF OVARIAN CANCER |
摘要 |
Drug delivery devices, medicaments, and methods are provided for the intraperitoneal treatment of ovarian cancer. An implantable device for drug delivery includes an elongated, flexible device having a housing defining a reservoir that contains a drug in solid or semi-solid form, and configured to be wholly deployed within the peritoneal cavity of a patient and continuously release a therapeutically effective amount of the drug over a period of at least 24 hours. A medicament includes cisplatin for administration into the peritoneal cavity of a patient continuously over a treatment period of at least 24 hours. A method of drug delivery includes implanting within the peritoneal cavity of a patient an elongated, flexible device having a reservoir containing a drug, solubilizing the drug at least in part with peritoneal fluid, and releasing an effective amount of the solubilized drug from the reservoir continuously for a period of at least 24 hours. |
申请公布号 |
WO2013170069(A1) |
申请公布日期 |
2013.11.14 |
申请号 |
WO2013US40405 |
申请日期 |
2013.05.09 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE GENERAL HOSPITAL CORPORATION |
发明人 |
CIMA, MICHAEL, J.;YE, HONGYE;DEL CARMEN, MARCELA;BIRRER, MICHAEL |
分类号 |
A61M31/00;A61K31/282;A61P35/00 |
主分类号 |
A61M31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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