摘要 |
Methods and compositions for improving the delivery and/or efficacy of a therapy (e.g., a cancer therapy) are disclosed. In one embodiment, methods and compositions for treating or preventing a cancer (e.g., a solid tumor such as a desmoplastic tumor) by administering to a subject an anti-hypertensive agent, as a single agent or in combination with a microenvironment modulator and/or a therapy, e.g., a cancer therapy (for example, a therapeutic agent or therapy, including immunotherapy (e.g., antibodies, vaccine, cell-based), nanotherapeutics, radiation therapy, photodynamic therapy, low molecular weight chemotherapeutics, molecularly targeted therapeutics and/or oxygen radical) are disclosed. |
申请人 |
THE GENERAL HOSPITAL CORPORATION;XTUIT PHARMACEUTICALS, INC.;JAIN, RAKESH, KUMAR;BOUCHER, YVES;CHAUHAN, VIKASH, PAL, SINGH;DIOP-FRIMPONG, BENJAMIN;KRANE, STEPHEN |
发明人 |
JAIN, RAKESH, KUMAR;BOUCHER, YVES;CHAUHAN, VIKASH, PAL, SINGH;DIOP-FRIMPONG, BENJAMIN;KRANE, STEPHEN;CRANE, ALANE, L.;LANGER, ROBERT, SAMUEL |