发明名称 METHOD FOR BONE TISSUE REGENERATION IN EXPERIMENTS
摘要 <p>The invention relates to the treatment of different bone injuries, particularly fractures and fissure fractures, and can be used in medical and veterinary therapy and surgery. In order to reduce the time taken for bone tissue to regenerate at the site of damage or a defect and to reduce the time taken for the normal physiological functioning of an injured bone to be restored, a method is used for regenerating bone tissue by fixing fragments of the damaged bone with a plaster cast or a bandage made of a polymer material and introducing into the fracture zone an aqueous solution containing 1-hydroxyethylidene diphosphonic acid in an amount of (1.80-2.06) g/l, anhydrous calcium chloride in an amount of (1.44-2.22) g/l, gadolinium (III) nitrate hexahydrate in an amount of (0.30-0.40) g/l and dysprosium (III) chloride hexahydrate in an amount of (0.038-0.076) g/l, with a pH of (7.3-7.8), wherein, prior to being introduced into the fracture zone, the above solution is brought to a temperature of (30-100)°?, is held at this temperature for (1-48) hours and is then cooled to room temperature. As a result, there is a significant (20-25%) reduction in the time taken for bone tissue to regenerate at the injury site, irrespective of the type of animal which has sustained the injury. The above-mentioned solution for injection has low toxicity and good storage properties and can be kept for an extended period of time without loss of activity.</p>
申请公布号 CA2873188(A1) 申请公布日期 2013.11.14
申请号 CA20132873188 申请日期 2013.04.26
申请人 DEVYATOV, FEDOR VLADIMIROVICH 发明人 DEVYATOV, FEDOR VLADIMIROVICH
分类号 A61K31/185;A61K33/00;A61P19/08 主分类号 A61K31/185
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