| 摘要 |
<p>A method for the manufacture of a capillary driven assay device, comprising the steps a) providing a capillary substrate, b) modifying the hydrophilicity of the surface of the substrate, c) mixing a matrix and a capturing molecule in a solution to obtain a solution comprising capturing molecules covalently bound to the matrix, and d) depositing the solution in a distinct area in the at least one retaining zone. A capillary driven assay device is obtainable by the method. Advantages of the invention include that it is possible to modify the substrate with one surface chemistry and still deposit capturing molecules in an optimal matrix on desired areas. Less matrix material is consumed, and thus several different matrix materials can be used on one chip. ( Fig. 2 )</p> |
