| 摘要 |
Cosmetic use of a hydroxylated amide compound (I) and its salts, isomers and solvates as a skin moisturizer. Cosmetic use of a hydroxylated amide compound (I) of formula R 4-O-CH 2-CH(OR 3>)-CH(OR 3>)-C(O)-NR 2>R 1> and its salts, isomers and solvates as a skin moisturizer. Either R 1>, R 2>H, 1-6C, preferably 3-6C alkyl (optionally substituted by -OR 5>-, -SiMe 3, -CO 2R 6 or -F); NR 1>R 2>5-7 membered hetero cycle (optionally containing another hetero atom such as S or O), e.g. pyrrolidine, piperidine, morpholine, thiomorpholine or cyclohexamethyleneimine (or homopiperidine), preferably pyrrolidine (optionally substituted by 1-3 groups (preferably 1 group) of 1-4C linear or 3-4C branched alkyl (optionally substituted by OH)); R 5>H or 1-3C linear, 3C branched or 2-3C unsaturated alkyl; R 6>H or 1-4C linear or 3-4C branched alkyl; either R 3>H or 1-6C alkyl; or 2R 3>isopropylidene; and either R 4>H or; OR 3>, OR 4>phosphate group. Independent claims are included for: (1) a composition comprising (I) and oils, waxes, thickening agents, polymer film, preservatives, perfumes, fillers, UV filters, microbicides, odor absorbers, dyestuffs, cosmetic active agents, plant extracts, antioxidants or surfactants; (2) method of non-therapeutic treatment and/or makeup of skin, comprising application of the composition on the skin; and (3) hydroxylated amide compound (I). - ACTIVITY : Dermatological. - MECHANISM OF ACTION : None given.
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