发明名称 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN IL-1.BETA.
摘要 The invention relates to an ahumanized antibody molecule having specificity for antigenic determinants of IL-1.beta., andwhich is made with CDRs from the murine antibody IC8 that are grafted into human frameworks. Methods for generating genes for grated sequence are also disclosed.
申请公布号 CA2515474(C) 申请公布日期 2013.11.12
申请号 CA20042515474 申请日期 2004.02.06
申请人 CELLTECH R & D LIMITED 发明人 LAWSON, ALASTAIR DAVID GRIFFITHS;POPPLEWELL, ANDREW GEORGE
分类号 C12N15/13;A61K39/395;A61K47/48;A61P29/00;C07K16/24;C12N5/10;C12N15/85;C12P21/08 主分类号 C12N15/13
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