发明名称 |
ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN IL-1.BETA. |
摘要 |
The invention relates to an ahumanized antibody molecule having specificity for antigenic determinants of IL-1.beta., andwhich is made with CDRs from the murine antibody IC8 that are grafted into human frameworks. Methods for generating genes for grated sequence are also disclosed.
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申请公布号 |
CA2515474(C) |
申请公布日期 |
2013.11.12 |
申请号 |
CA20042515474 |
申请日期 |
2004.02.06 |
申请人 |
CELLTECH R & D LIMITED |
发明人 |
LAWSON, ALASTAIR DAVID GRIFFITHS;POPPLEWELL, ANDREW GEORGE |
分类号 |
C12N15/13;A61K39/395;A61K47/48;A61P29/00;C07K16/24;C12N5/10;C12N15/85;C12P21/08 |
主分类号 |
C12N15/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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