发明名称 PRODUCTION AND USE OF RECOMBINANT PROTEIN MULTIMERS WITH ALTERED BIOLOGICAL ACTIVITY
摘要 The invention relates to recombinant fusion proteins, either with or without peptide linkers, with or without variations in noncoding regions of the protein. The fusion proteins have altered structural and functional properties and biological activity. The fusion proteins can be used, for example, as in vivo therapeutics.
申请公布号 CA2296071(C) 申请公布日期 2013.11.12
申请号 CA19982296071 申请日期 1998.07.09
申请人 BETH ISRAEL DEACONESS MEDICAL CENTER 发明人 SYTKOWSKI, ARTHUR J.
分类号 C12N15/09;C12N15/62;A61K38/00;A61K38/18;A61K38/22;A61P7/06;C07K14/505;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/18;C12N15/85 主分类号 C12N15/09
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