发明名称 |
Modulation of forkhead box O1A expression |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of forkhead box O1A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding forkhead box O1A. Methods of using these compounds for modulation of forkhead box O1A expression and for treatment of diseases associated with expression of forkhead box O1A are provided, in particular, for methods of treating diabetes.
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申请公布号 |
US8580948(B2) |
申请公布日期 |
2013.11.12 |
申请号 |
US201213531087 |
申请日期 |
2012.06.22 |
申请人 |
DOBIE KENNETH W.;BHANOT SANJAY;MCKAY ROBERT;PANDEY SANJAY K.;ISIS PHARMACEUTICALS, INC. |
发明人 |
DOBIE KENNETH W.;BHANOT SANJAY;MCKAY ROBERT;PANDEY SANJAY K. |
分类号 |
C07H21/04;A61K38/00;C12N15/113 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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