发明名称 |
Peptide-coated cell localization to diseased or damaged tissues and methods related thereto |
摘要 |
Embodiments of the present invention are directed to a coated cell comprising a therapeutic cell and a plurality of targeting complexes coating the therapeutic cell and each of said targeting complexes comprising a homing molecule, a lipid moiety, and a spacer having from about 1 to about 10 amino acids and covalently linking the homing molecule to the lipid moiety and wherein the lipid moiety is non-covalently attached to the therapeutic cell. In some embodiments, the therapeutic cell is a stem cell. Embodiments of the invention are directed to methods of coating a therapeutic cell. Embodiments of the invention are directed to methods of treating diseases of the vasculature. |
申请公布号 |
US8580749(B2) |
申请公布日期 |
2013.11.12 |
申请号 |
US20100795195 |
申请日期 |
2010.06.07 |
申请人 |
WAGNER JOSEPH;YOUNG RANDELL;FINK DAVID;CELL TARGETING, INC. |
发明人 |
WAGNER JOSEPH;YOUNG RANDELL;FINK DAVID |
分类号 |
A61K38/08 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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